SERS aptasensor from nanorod-nanoparticle junction for protein detection.

نویسندگان

  • Yuling Wang
  • Kyuwan Lee
  • Joseph Irudayaraj
چکیده

A multicomponent nanostructure comprising of gold nanorod-nanoparticle (AuNR-AuNP) composites was fabricated to detect thrombin at subnanomolar concentrations in diluted human blood serum. Simulation and experiments revealed that the strong electromagnetic coupling resonance at the nanorod-nanoparticle junction of these probes can be used to construct highly sensitive SERS aptasensors.

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عنوان ژورنال:
  • Chemical communications

دوره 46 4  شماره 

صفحات  -

تاریخ انتشار 2010